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According to a recent Fortune Small Business article, the best way to run Microsoft Office is on a Mac. The article talks about some of the advantages and disadvantages of running Office on a Mac vs. a PC.
The article is worth a read if your small business is interested in running Office 2008 or perhaps even introducing Macs into your environment. The article does include one FUD quote however: “And if you use Web-based office productivity tools like Google Apps, Basecamp or Zoho, expect trouble. In my testing, pages just sometimes wouldn’t load or render properly. We never could figure out why.” I’m not sure what Jonathan Blum (the author) was doing, but using these sites in Firefox on my Mac works just fine.